Chapter XIV

Diseases of the genitourinary system

Renal tubulo-interstitial diseases

Includes: pyelonephritis
Excludes: pyeloureteritis cystica ( N28.8 )

N10 Acute tubulo-interstitial nephritis
· infectious interstitial nephritis
· pyelitis
· pyelonephritis
Use additional code (B95-B97), if desired, to identify infectious agent.

N11 Chronic tubulo-interstitial nephritis
Includes: chronic:
· infectious interstitial nephritis
· pyelitis
· pyelonephritis
Use additional code (B95-B97), if desired, to identify infectious agent.
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
Pyelonephritis (chronic) associated with (vesicoureteral) reflux
Excludes: vesicoureteral reflux NOS ( N13.7 )
N11.1 Chronic obstructive pyelonephritis
Pyelonephritis (chronic) associated with:
· anomaly
· kinking
· obstruction
· stricture
pelviureteric junction
pyeloureteric junction
Excludes: calculous pyelonephritis ( N20.9 )
obstructive uropathy ( N13.- )
N11.8 Other chronic tubulo-interstitial nephritis
Nonobstructive chronic pyelonephritis NOS
N11.9 Chronic tubulo-interstitial nephritis, unspecified
· interstitial nephritis NOS
· pyelitis NOS
· pyelonephritis NOS

N12 Tubulo-interstitial nephritis, not specified as acute or chronic
Interstitial nephritis NOS
Pyelitis NOS
Pyelonephritis NOS
Excludes: calculous pyelonephritis ( N20.9 )

N13 Obstructive and reflux uropathy
Excludes: calculus of kidney and ureter without hydronephrosis ( N20.- )
congenital obstructive defects of renal pelvis and ureter ( Q62.0-Q62.3 )
obstructive pyelonephritis ( N11.1 )
N13.0 Hydronephrosis with ureteropelvic junction obstruction
Excludes: with infection ( N13.6 )
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
Excludes: with infection ( N13.6 )
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
Excludes: with infection ( N13.6 )
N13.3 Other and unspecified hydronephrosis
Excludes: with infection ( N13.6 )
N13.4 Hydroureter
Excludes: with infection ( N13.6 )
N13.5 Kinking and stricture of ureter without hydronephrosis
Excludes: with infection ( N13.6 )
N13.6 Pyonephrosis
Conditions in N13.0-N13.5 with infection
Obstructive uropathy with infection
Use additional code (B95-B97), if desired, to identify infectious agent.
N13.7 Vesicoureteral-reflux-associated uropathy
Vesicoureteral reflux:
· with scarring
Excludes: reflux-associated pyelonephritis ( N11.0 )
N13.8 Other obstructive and reflux uropathy
N13.9 Obstructive and reflux uropathy, unspecified
Urinary tract obstruction NOS

N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
Use additional external cause code (Chapter XX), if desired, to identify toxic agent.
N14.0 Analgesic nephropathy
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
N14.3 Nephropathy induced by heavy metals
N14.4 Toxic nephropathy, not elsewhere classified

N15 Other renal tubulo-interstitial diseases
N15.0 Balkan nephropathy
Balkan endemic nephropathy
N15.1 Renal and perinephric abscess
N15.8 Other specified renal tubulo-interstitial diseases
N15.9 Renal tubulo-interstitial disease, unspecified
Infection of kidney NOS
Excludes: urinary tract infection NOS ( N39.0 )

N16* Renal tubulo-interstitial disorders in diseases classified elsewhere
N16.0* Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
Renal tubulo-interstitial disorders (due to)(in):
· brucellosis ( A23.-+ )
· diphtheria ( A36.8+ )
· salmonella infection ( A02.2+ )
· septicaemia ( A40-A41+ )
· toxoplasmosis ( B58.8+ )
N16.1* Renal tubulo-interstitial disorders in neoplastic diseases
Renal tubulo-interstitial disorders in:
· leukaemia ( C91-C95+ )
· lymphoma ( C81-C85+ , C96.-+ )
· multiple myeloma ( C90.0+ )
N16.2* Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
Renal tubulo-interstitial disorders in:
· mixed cryoglobulinaemia ( D89.1+ )
· sarcoidosis ( D86.-+ )
N16.3* Renal tubulo-interstitial disorders in metabolic diseases
Renal tubulo-interstitial disorders in:
· cystinosis ( E72.0+ )
· glycogen storage disease ( E74.0+ )
· Wilson's disease ( E83.0+ )
N16.4* Renal tubulo-interstitial disorders in systemic connective tissue disorders
Renal tubulo-interstitial disorders in:
· sicca syndrome [Sjögren] ( M35.0+ )
· systemic lupus erythematosus ( M32.1+ )
N16.5* Renal tubulo-interstitial disorders in transplant rejection ( T86.-+ )
N16.8* Renal tubulo-interstitial disorders in other diseases classified elsewhere