Chapter XIV
Diseases of the genitourinary system
(N00-N99)

Glomerular diseases
(N00-N08)

Use additional code, if desired, to identify external cause (Chapter XX) or presence of renal failure (N17-N19).
Excludes: hypertensive renal disease ( I12.- )
The following fourth-character subdivisions classify morphological changes and are for use with categories N00-N07. Subdivisions .0-.8 should not normally be used unless these have been specifically identified (e.g. by renal biopsy or autopsy). The three-character categories relate to clinical syndromes.
.0 Minor glomerular abnormality
Minimal change lesion
.1 Focal and segmental glomerular lesions
Focal and segmental:
· hyalinosis
· sclerosis
Focal glomerulonephritis
.2 Diffuse membranous glomerulonephritis
.3 Diffuse mesangial proliferative glomerulonephritis
.4 Diffuse endocapillary proliferative glomerulonephritis
.5 Diffuse mesangiocapillary glomerulonephritis
Membranoproliferative glomerulonephritis, types 1 and 3, or NOS
.6 Dense deposit disease
Membranoproliferative glomerulonephritis, type 2
.7 Diffuse crescentic glomerulonephritis
Extracapillary glomerulonephritis
.8 Other
Proliferative glomerulonephritis NOS
.9 Unspecified

N00 Acute nephritic syndrome
[See before N00 for subdivisions ]
Includes: acute:
· glomerular disease
· glomerulonephritis
· nephritis
· renal disease NOS
Excludes: acute infectious tubulo-interstitial nephritis ( N10 )
nephritic syndrome NOS ( N05.- )

N01 Rapidly progressive nephritic syndrome
[See before N00 for subdivisions ]
Includes: rapidly progressive:
· glomerular disease
· glomerulonephritis
· nephritis
Excludes: nephritic syndrome NOS ( N05.- )

N02 Recurrent and persistent haematuria
[See before N00 for subdivisions ]
Includes: haematuria:
· benign (familial)(of childhood)
· with morphological lesion specified in .0-.8 before N00.-
Excludes: haematuria NOS ( R31 )

N03 Chronic nephritic syndrome
[See before N00 for subdivisions ]
Includes: chronic:
· glomerular disease
· glomerulonephritis
· nephritis
· renal disease NOS
Excludes: chronic tubulo-interstitial nephritis ( N11.- )
diffuse sclerosing glomerulonephritis ( N18.- )
nephritic syndrome NOS ( N05.- )

N04 Nephrotic syndrome
[See before N00 for subdivisions ]
Includes: congenital nephrotic syndrome
lipoid nephrosis

N05 Unspecified nephritic syndrome
[See before N00 for subdivisions ]
Includes: glomerular disease
glomerulonephritis
nephritis
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NOS
nephropathy NOS and renal disease NOS with morphological lesion specified in .0-.8 before N00.-
Excludes: nephropathy NOS with no stated morphological lesion ( N28.9 )
renal disease NOS with no stated morphological lesion ( N28.9 )
tubulo-interstitial nephritis NOS ( N12 )

N06 Isolated proteinuria with specified morphological lesion
[See before N00 for subdivisions ]
Includes: proteinuria (isolated)(orthostatic)(persistent) with morphological lesion specified in .0-.8 before N00.-
Excludes: proteinuria:
· NOS ( R80 )
· Bence Jones ( R80 )
· gestational ( O12.1 )
· isolated NOS ( R80 )
· orthostatic NOS ( N39.2 )
· persistent NOS ( N39.1 )

N07 Hereditary nephropathy, not elsewhere classified
[See before N00 for subdivisions ]
Excludes: Alport's syndrome ( Q87.8 )
hereditary amyloid nephropathy ( E85.0 )
nail patella syndrome ( Q87.2 )
non-neuropathic heredofamilial amyloidosis ( E85.0 )

N08* Glomerular disorders in diseases classified elsewhere
Includes: nephropathy in diseases classified elsewhere
Excludes: renal tubulo-interstitial disorders in diseases classified elsewhere ( N16.-* )
N08.0* Glomerular disorders in infectious and parasitic diseases classified elsewhere
Glomerular disorders in:
· Plasmodium malariae malaria ( B52.0+ )
· mumps ( B26.8+ )
· schistosomiasis [bilharziasis] ( B65.-+ )
· septicaemia ( A40-A41+ )
· strongyloidiasis ( B78.-+ )
· syphilis ( A52.7+ )
N08.1* Glomerular disorders in neoplastic diseases
Glomerular disorders in:
· multiple myeloma ( C90.0+ )
· Waldenström's macroglobulinaemia ( C88.0+ )
N08.2* Glomerular disorders in blood diseases and disorders involving the immune mechanism
Glomerular disorders in:
· cryoglobulinaemia ( D89.1+ )
· disseminated intravascular coagulation [defibrination syndrome] ( D65+ )
· haemolytic-uraemic syndrome ( D59.3+ )
· Henoch(-Schönlein) purpura ( D69.0+ )
· sickle-cell disorders ( D57.-+ )
N08.3* Glomerular disorders in diabetes mellitus ( E10-E14+ with common fourth character .2)
N08.4* Glomerular disorders in other endocrine, nutritional and metabolic diseases
Glomerular disorders in:
· amyloidosis ( E85.-+ )
· Fabry(-Anderson) disease ( E75.2+ )
· lecithin cholesterol acyltransferase deficiency ( E78.6+ )
N08.5* Glomerular disorders in systemic connective tissue disorders
Glomerular disorders in:
· Goodpasture's syndrome ( M31.0+ )
· microscopic polyangiitis ( M31.7+ )
· systemic lupus erythematosus ( M32.1+ )
· thrombotic thrombocytopenic purpura ( M31.1+ )
· Wegener's granulomatosis ( M31.3+ )
N08.8* Glomerular disorders in other diseases classified elsewhere
Glomerular disorders in subacute bacterial endocarditis ( I33.0+ )