Chapter IV

Endocrine, nutritional and metabolic diseases

Disorders of thyroid gland

E00 Congenital iodine-deficiency syndrome
Includes: endemic conditions associated with environmental iodine deficiency either directly or as a consequence of maternal iodine deficiency. Some of the conditions have no current hypothyroidism but are the consequence of inadequate thyroid hormone secretion in the developing fetus. Environmental goitrogens may be associated.
Use additional code (F70-F79), if desired, to identify associated mental retardation.
Excludes: subclinical iodine-deficiency hypothyroidism ( E02 )
E00.0 Congenital iodine-deficiency syndrome, neurological type
Endemic cretinism, neurological type
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
Endemic cretinism:
· hypothyroid
· myxoedematous type
E00.2 Congenital iodine-deficiency syndrome, mixed type
Endemic cretinism, mixed type
E00.9 Congenital iodine-deficiency syndrome, unspecified
Congenital iodine-deficiency hypothyroidism NOS
Endemic cretinism NOS

E01 Iodine-deficiency-related thyroid disorders and allied conditions
Excludes: congenital iodine-deficiency syndrome ( E00.- )
subclinical iodine-deficiency hypothyroidism ( E02 )
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
Iodine-deficiency-related nodular goitre
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
Endemic goitre NOS
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
Acquired iodine-deficiency hypothyroidism NOS

E02 Subclinical iodine-deficiency hypothyroidism

E03 Other hypothyroidism
Excludes: iodine-deficiency-related hypothyroidism ( E00-E02)
postprocedural hypothyroidism ( E89.0)
E03.0 Congenital hypothyroidism with diffuse goitre
Goitre (nontoxic) congenital:
· parenchymatous
Excludes: transitory congenital goitre with normal function ( P72.0)
E03.1 Congenital hypothyroidism without goitre
Aplasia of thyroid (with myxoedema)
· atrophy of thyroid
· ectopic thyropid
· hypothyroidism NOS
E03.2 Hypothyroidism due to medicaments and other exogenous substances
Use additional external cause code (Chapter XX), if desired, to identify cause.
E03.3 Postinfectious hypothyroidism
E03.4 Atrophy of thyroid (acquired)
Excludes: congenital atrophy of thyroid ( E03.1)
E03.5 Myxoedema coma
#E03.6 Hypothyroidism from Hashimoto's thyroiditis
E03.8 Other specified hypothyroidism
Hypothyroidism from transient thyroiditis
E03.9 Hypothyroidism, unspecified
Myxoedema NOS

E04 Other nontoxic goitre
Excludes: congenital goitre:
· diffuse
· parenchymatous
( E03.0 )
iodine-deficiency-related goitre ( E00-E02 )
E04.0 Nontoxic diffuse goitre
Goitre, nontoxic:
· diffuse (colloid)
· simple
E04.1 Nontoxic single thyroid nodule
Colloid nodule (cystic)(thyroid)
Nontoxic uninodular goitre
Thyroid (cystic) nodule NOS
E04.2 Nontoxic multinodular goitre
Cystic goitre NOS
Multinodular (cystic) goitre NOS
E04.8 Other specified nontoxic goitre
E04.9 Nontoxic goitre, unspecified
Goitre NOS
Nodular goitre (nontoxic) NOS

E05 Thyrotoxicosis [hyperthyroidism]
Excludes: chronic thyroiditis with transient thyrotoxicosis ( E06.2 )
neonatal thyrotoxicosis ( P72.1 )
E05.0 Thyrotoxicosis with diffuse goitre
Exophthalmic or toxic goitre NOS
Graves' disease
Toxic diffuse goitre
E05.1 Thyrotoxicosis with toxic single thyroid nodule
Thyrotoxicosis with toxic uninodular goitre
E05.2 Thyrotoxicosis with toxic multinodular goitre
Toxic nodular goitre NOS
E05.3 Thyrotoxicosis from ectopic thyroid tissue
E05.4 Thyrotoxicosis factitia
E05.5 Thyroid crisis or storm
E05.8 Other thyrotoxicosis
Overproduction of thyroid-stimulating hormone
Use additional external cause code (Chapter XX), if desired, to identify cause.
E05.9 Thyrotoxicosis, unspecified
Hyperthyroidism NOS
Thyrotoxic heart disease+ ( I43.8* )

E06 Thyroiditis
Excludes: postpartum thyroiditis ( O90.5)
E06.0 Acute thyroiditis
Abscess of thyroid
· pyogenic
· suppurative
Use additional code (B95-B97), if desired, to identify infectious agent.
E06.1 Subacute thyroiditis
· de Quervain
· giant-cell
· granulomatous
· nonsuppurative
Excludes: autoimmune thyroiditis ( E06.3)
E06.2 Chronic thyroiditis with transient thyrotoxicosis
Excludes: autoimmune thyroiditis ( E06.3)
E06.3 Autoimmune thyroiditis
Hashimoto's thyroiditis
Hashitoxicosis (transient)
Lymphadenoid goitre
Lymphocytic thyroiditis
Struma lymphomatosa
E06.4 Drug-induced thyroiditis
Use additional external cause code (Chapter XX), if desired, to identify drug.
E06.5 Other chronic thyroiditis
· chronic:
  · NOS
  · fibrous
· ligneous
· Riedel
# E06.6 Transient painless thyroiditis, sporadic
E06.9 Thyroiditis, unspecified

E07 Other disorders of thyroid
E07.0 Hypersecretion of calcitonin
C-cell hyperplasia of thyroid
Hypersecretion of thyrocalcitonin
E07.1 Dyshormogenetic goitre
Familial dyshormogenetic goitre
Pendred's syndrome
Excludes: transitory congenital goitre with normal function ( P72.0)
#E07.2 Thyroid hormone resistant syndrome
#E07.3 Euthyroid hyperthyroxinaemia
E07.8 Other specified disorders of thyroid
Abnormality of thyroid-binding globulin
of thyroid
Sick-euthyroid syndrome [non thyroidal illness]
E07.9 Disorder of thyroid, unspecified