Chapter II

Neoplasms
(C00-D48)

In situ neoplasms
(D00-D09)

Note: Many in situ neoplasms are regarded as being located within a continuum of morphological change between dysplasia and invasive cancer. For example, for cervical intraepithelial neoplasia (CIN) three grades are recognized, the third of which (CIN III) includes both severe dysplasia and carcinoma in situ. This system of grading has been extended to other organs, such as vulva and vagina. Descriptions of grade III intraepithelial neoplasia, with or without mention of severe dysplasia, are assigned to this section; grades I and II are classified as dysplasia of the organ system involved and should be coded to the relevant body system chapter.
Includes: Bowen's disease
erythroplasia
morphology codes with behaviour code /2
Queyrat's erythroplasia

D00 Carcinoma in situ of oral cavity, oesophagus and stomach
Excludes: melanoma in situ ( D03.- )
D00.0 Lip, oral cavity and pharynx
Aryepiglottic fold:
· NOS
· hypopharyngeal aspect
· marginal zone
Vermilion border of lip
Excludes: aryepiglottic fold, laryngeal aspect ( D02.0 )
epiglottis:
· NOS ( D02.0 )
· suprahyoid portion ( D02.0 )
skin of lip ( D03.0 , D04.0 )
D00.1 Oesophagus
D00.2 Stomach

D01 Carcinoma in situ of other and unspecified digestive organs
Excludes: melanoma in situ ( D03.- )
D01.0 Colon
Excludes: rectosigmoid junction ( D01.1 )
D01.1 Rectosigmoid junction
D01.2 Rectum
D01.3 Anus and anal canal
Excludes: anal:
· margin ( D03.5 , D04.5 )
· skin ( D03.5 , D04.5 )
perianal skin ( D03.5 , D04.5 )
D01.4 Other and unspecified parts of intestine
Excludes: ampulla of Vater ( D01.5 )
D01.5 Liver, gallbladder and bile ducts
Ampulla of Vater
D01.7 Other specified digestive organs
Pancreas
D01.9 Digestive organ, unspecified

D02 Carcinoma in situ of middle ear and respiratory system
Excludes: melanoma in situ ( D03.- )
D02.0 Larynx
Aryepiglottic fold, laryngeal aspect
Epiglottis (suprahyoid portion)
Excludes: aryepiglottic fold:
· NOS ( D00.0 )
· hypopharyngeal aspect ( D00.0 )
· marginal zone ( D00.0 )
D02.1 Trachea
D02.2 Bronchus and lung
D02.3 Other parts of respiratory system
Accessory sinuses
Middle ear
Nasal cavities
Excludes: ear (external)(skin) ( D03.2 , D04.2 )
nose:
· NOS ( D09.7 )
· skin ( D03.3 , D04.3 )
D02.4 Respiratory system, unspecified

D03 Melanoma in situ
Includes: morphology codes M872-M879 with behaviour code /2
D03.0 Melanoma in situ of lip
D03.1 Melanoma in situ of eyelid, including canthus
D03.2 Melanoma in situ of ear and external auricular canal
D03.3 Melanoma in situ of other and unspecified parts of face
D03.4 Melanoma in situ of scalp and neck
D03.5 Melanoma in situ of trunk
Anal:
· margin
· skin
Breast (skin)(soft tissue)
Perianal skin
D03.6 Melanoma in situ of upper limb, including shoulder
D03.7 Melanoma in situ of lower limb, including hip
D03.8 Melanoma in situ of other sites
D03.9 Melanoma in situ, unspecified

D04 Carcinoma in situ of skin
Excludes: erythroplasia of Queyrat (penis) NOS ( D07.4 )
melanoma in situ ( D03.- )
D04.0 Skin of lip
Excludes: vermilion border of lip ( D00.0 )
D04.1 Skin of eyelid, including canthus
D04.2 Skin of ear and external auricular canal
D04.3 Skin of other and unspecified parts of face
D04.4 Skin of scalp and neck
D04.5 Skin of trunk
Anal:
· margin
· skin
Perianal skin
Skin of breast
Excludes: anus NOS ( D01.3 )
skin of genital organs ( D07.- )
D04.6 Skin of upper limb, including shoulder
D04.7 Skin of lower limb, including hip
D04.8 Skin of other sites
D04.9 Skin, unspecified

D05 Carcinoma in situ of breast
Excludes: carcinoma in situ of skin of breast ( D04.5 )
melanoma in situ of breast (skin) ( D03.5 )
D05.0 Lobular carcinoma in situ
D05.1 Intraductal carcinoma in situ
D05.7 Other carcinoma in situ of breast
D05.9 Carcinoma in situ of breast, unspecified

D06 Carcinoma in situ of cervix uteri
Includes: cervical intraepithelial neoplasia [CIN], grade III, with or without mention of severe dysplasia
Excludes: melanoma in situ of cervix ( D03.5 )
severe dysplasia of cervix NOS ( N87.2 )
D06.0 Endocervix
D06.1 Exocervix
D06.7 Other parts of cervix
D06.9 Cervix, unspecified

D07 Carcinoma in situ of other and unspecified genital organs
Excludes: melanoma in situ ( D03.5 )
D07.0 Endometrium
D07.1 Vulva
Vulvar intraepithelial neoplasia [VIN], grade III, with or without mention of severe dysplasia
Excludes: severe dysplasia of vulva NOS ( N90.2 )
D07.2 Vagina
Vaginal intraepithelial neoplasia [VAIN], grade III, with or without mention of severe dysplasia
Excludes: severe dysplasia of vagina NOS ( N89.2 )
D07.3 Other and unspecified female genital organs
D07.4 Penis
Erythroplasia of Queyrat NOS
D07.5 Prostate
D07.6 Other and unspecified male genital organs

D09 Carcinoma in situ of other and unspecified sites
Excludes: melanoma in situ ( D03.- )
D09.0 Bladder
D09.1 Other and unspecified urinary organs
D09.2 Eye
Excludes: skin of eyelid ( D04.1 )
D09.3 Thyroid and other endocrine glands
Excludes: endocrine pancreas ( D01.7 )
ovary ( D07.3 )
testis ( D07.6 )
D09.7 Carcinoma in situ of other specified sites
D09.9 Carcinoma in situ, unspecified