Chapter II

Neoplasms
(C00-D48)

Malignant neoplasms
(C00-C97)

Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic and related tissue
(C00-C75)

Malignant neoplasms of digestive organs
(C15-C26)

C15 Malignant neoplasm of oesophagus
Note: Two alternative subclassifications are given:
  • .0-.2 by anatomical description
  • .3-.5 by thirds

This departure from the principle that categories should be mutually exclusive is deliberate, since both forms of terminology are in use but the resulting anatomical divisions are not analogous.

C15.0 Cervical part of oesophagus
C15.1 Thoracic part of oesophagus
C15.2 Abdominal part of oesophagus
C15.3 Upper third of oesophagus
C15.4 Middle third of oesophagus
C15.5 Lower third of oesophagus
C15.8 Overlapping lesion of oesophagus
[See note 5 at the beginning of this chapter]
C15.9 Oesophagus, unspecified

C16 Malignant neoplasm of stomach
C16.0 Cardia
Cardiac orifice
Cardio-oesophageal junction
Gastro-oesophageal junction
Oesophagus and stomach
C16.1 Fundus of stomach
C16.2 Body of stomach
C16.3 Pyloric antrum
Gastric antrum
C16.4 Pylorus
Prepylorus
Pyloric canal
C16.5 Lesser curvature of stomach, unspecified
Lesser curvature of stomach, not classifiable to C16.1-C16.4
C16.6 Greater curvature of stomach, unspecified
Greater curvature of stomach, not classifiable to C16.0-C16.4
C16.8 Overlapping lesion of stomach
[See note 5 at the beginning of this chapter]
C16.9 Stomach, unspecified
Gastric cancer NOS

C17 Malignant neoplasm of small intestine
C17.0 Duodenum
C17.1 Jejunum
C17.2 Ileum
Excludes: ileocaecal valve ( C18.0 )
C17.3 Meckel's diverticulum
C17.8 Overlapping lesion of small intestine
[See note 5 at the beginning of this chapter]
C17.9 Small intestine, unspecified

C18 Malignant neoplasm of colon
C18.0 Caecum
Ileocaecal valve
C18.1 Appendix
C18.2 Ascending colon
C18.3 Hepatic flexure
C18.4 Transverse colon
C18.5 Splenic flexure
C18.6 Descending colon
C18.7 Sigmoid colon
Sigmoid (flexure)
Excludes: rectosigmoid junction ( C19 )
C18.8 Overlapping lesion of colon
[See note 5 at the beginning of this chapter]
C18.9 Colon, unspecified
Large intestine NOS

C19 Malignant neoplasm of rectosigmoid junction
Colon with rectum
Rectosigmoid (colon)

C20 Malignant neoplasm of rectum
Rectal ampulla

C21 Malignant neoplasm of anus and anal canal
C21.0 Anus, unspecified
Excludes: anal:
· margin ( C43.5 , C44.5 )
· skin ( C43.5 , C44.5 )
perianal skin ( C43.5 , C44.5 )
C21.1 Anal canal
Anal sphincter
C21.2 Cloacogenic zone
C21.8 Overlapping lesion of rectum, anus and anal canal
[See note 5 at the beginning of this chapter]
Anorectal junction
Anorectum
Malignant neoplasm of rectum, anus and anal canal whose point of origin cannot be classified to any one of the categories C20-C21.2

C22 Malignant neoplasm of liver and intrahepatic bile ducts
Excludes: biliary tract NOS ( C24.9 )
secondary malignant neoplasm of liver ( C78.7 )
C22.0 Liver cell carcinoma
Hepatocellular carcinoma
Hepatoma
C22.1 Intrahepatic bile duct carcinoma
Cholangiocarcinoma
C22.2 Hepatoblastoma
C22.3 Angiosarcoma of liver
Kupffer cell sarcoma
C22.4 Other sarcomas of liver
C22.7 Other specified carcinomas of liver
C22.9 Liver, unspecified

C23 Malignant neoplasm of gallbladder

C24 Malignant neoplasm of other and unspecified parts of biliary tract
Excludes: intrahepatic bile duct ( C22.1 )
C24.0 Extrahepatic bile duct
Biliary duct or passage NOS
Common bile duct
Cystic duct
Hepatic duct
C24.1 Ampulla of Vater
C24.8 Overlapping lesion of biliary tract
[See note 5 at the beginning of this chapter]
Malignant neoplasm involving both intrahepatic and extrahepatic bile ducts
Malignant neoplasm of biliary tract whose point of origin cannot be classified to any one of the categories C22.0-C24.1
C24.9 Biliary tract, unspecified

C25 Malignant neoplasm of pancreas
C25.0 Head of pancreas
C25.1 Body of pancreas
C25.2 Tail of pancreas
C25.3 Pancreatic duct
C25.4 Endocrine pancreas
Islets of Langerhans
C25.7 Other parts of pancreas
Neck of pancreas
C25.8 Overlapping lesion of pancreas
[See note 5 at the beginning of this chapter]
C25.9 Pancreas, unspecified

C26 Malignant neoplasm of other and ill-defined digestive organs
Excludes: peritoneum and retroperitoneum ( C48.- )
C26.0 Intestinal tract, part unspecified
Intestine NOS
C26.1 Spleen
Excludes: Hodgkin's disease ( C81.- )
non-Hodgkin's lymphoma ( C82-C85 )
C26.8 Overlapping lesion of digestive system
[See note 5 at the beginning of this chapter]
Malignant neoplasm of digestive organs whose point of origin cannot be classified to any one of the categories C15-C26.1
Excludes: cardio-oesophageal junction ( C16.0 )
C26.9 Ill-defined sites within the digestive system
Alimentary canal or tract NOS
Gastrointestinal tract NOS